The art of cold email: This is how your messages stand out from 95% of B2B spam

Moritz Heininger/June 7th, 2025

The sad truth about cold emails in 2025

Let's be honest: Most cold emails are terrible. Your inbox is probably full of them — generic messages that pretend to be personalized but are really just superficial templates with your name and job title.

You know the symptoms:
“I've seen you work as a marketing manager at XYZ...”
“After looking at your LinkedIn profile...”
“I noticed that you studied at the University of Hamburg...”

That kind of “personalization” isn't. It is useless at best and counterproductive at worst. Your potential customers already know where they work and what they've studied — mirroring this information to them doesn't add any value and just signals: “I've looked at your LinkedIn profile for 30 seconds.”

At Scalantec, we've researched and set up hundreds of B2B outreach campaigns. Our finding: There is a fundamental difference between emails that have a positive response rate of less than 1% and those that receive up to 8% positive replies on average. (By the way: If an agency promises you 20-30% average response rate — RUN! That is simply dubious.)

3 principles of convincing cold emails

Before we get into detail, three basic principles that every successful cold email should follow:

1. Relevance beats personalization

True personalization doesn't mean repeating obvious facts. It means providing relevant insights that show that you understand the recipient's specific situation.

Weak: “I've seen that you're responsible for the e-commerce division at Company X...”

Strong: “When analyzing your shipping structure, I noticed that you currently work with DHL and Hermes, but use separate carriers for shipments over 5kg — which could lead to margin problems, especially for product category Y, given your average shopping cart value of 89€.”

2. Evidence before allegation

Anyone can claim to be the best or to be able to solve problems. But only a few can prove it — especially in a first message.

Weak: “We have the best solution for e-commerce logistics and can reduce your costs.”

Strong: “For an online shop with a similar range of products (Home & Living, 2500+ SKUs), we were able to reduce shipping costs by 18% and reduce delivery time by an average of 1.3 days.”

3. Clear, low-threshold call-to-actions

Your goal with a first cold email isn't immediate sales or a 60-minute meeting. It is the start of a conversation.

Weak: “Here is my Calendly link to book an appointment for a demo.”

Strong: “Does it make sense to briefly discuss whether the method that worked for Shop Y could also be relevant for you?”

The anatomy of a perfect cold email

Now it's getting specific. A convincing cold email consists of five elements, which should be structured in this order:

1. The hook: Show real research and relevance

The first step is to read or delete. He must immediately show that this email was researched and written specifically for the recipient.

Example of a customer who sells to pharmaceutical companies: “In your latest annual report, I saw that the oncology study with the active ingredient XB478 was successfully completed from phase 2 to phase 3. This means that you are currently looking for suitable volunteers to complete your clinical trial. I see that you are responsible for oncology studies at AstraZeneca.”

This intro shows:

  • You've read the annual report and found really relevant information
  • You know their specific products/active ingredients
  • You understand the contact person's background
  • You understand their current challenges

2. The problem: Concretely and with context

After the hook, you define a specific problem that is relevant to the recipient — ideally one that emerges from your research and is not obvious.

Example of a tech newsletter customer: “I've noticed that your competitors like XYZ and ABC are increasingly advertising DevOps tools and cloud security solutions in their newsletters (issues dated 12/03 and 27/2) — a segment that is still underrepresented in your current content mix but is currently in high demand among tech decision makers.”

3. Credibility: Specific results or references

Support your claims with an appropriate, concise example or relevant reference.

Tech newsletter/podcast example: “The tech SaaS provider SuperTech generated 39 qualified customer meetings within three months through advertising in a newsletter with a target group similar to yours (tech decision makers in companies with 500 employees or more) and was able to reduce its CAC by 27% — while maintaining the same conversion rate.”

4. The CTA: Low-threshold and specific

The last step: A clear, easy-to-answer call to action that isn't a big commitment.

example: “Would it be helpful if I send you a brief analysis of how your current shipping mix performs compared to similar stores in your price range?”
or
“Does it make sense to briefly (10 min.) discuss whether our method could also work for your specific product range?”

Practical examples: This is how deep, relevant personalization works

Let's leave the theory behind and look at what in-depth research and real personalization look like in various industries in practice:

E-commerce/logistics

Weak personalization: “I've seen that you run an online shop and certainly want to optimize shipping costs...”

Strong personalization: “When analyzing your shop, I noticed that you are currently shipping with DHL and Hermes (API integration via Shopify). With your product category (premium cosmetics) and average shopping cart value (92€ according to Similar Web), we often see a problem with damaged shipments, especially with glass products such as your new serum series.”

Why it works: The sender shows that he has analyzed the shop in detail — from technical integration to shipping partners to specific products and shopping cart metrics.

Pharma/Clinical Trials

Weak personalization: “As a leading pharmaceutical company, you are safely conducting clinical trials and looking for more efficient ways to recruit patients...”

Strong personalization: “In your current phase III study for the JAK inhibitor PRX-672 (NCT identifier: NCT3842671), the recruitment rate is 37% below schedule, according to the EU Clinical Trials Register. This appears to be a challenge, particularly for hard-to-find patients who do not respond to TNF-alpha inhibitors — a pattern that we have also observed with similar compounds such as filgotinib and upadacitinib.”

Why it works: The sender shows profound expertise both about the company's specific study (including official identifier) as well as about the drug class and typical recruitment problems.

Tech Newsletters

Weak personalization: “I have subscribed to your newsletter and find it very interesting...”

Strong personalization: “In your last three newsletter issues (week 8-10), you have placed a strong focus on front-end technologies (React, Next.js, TailwindCSS), while your competitors such as' TechCrunch 'and 'The Changelog are increasingly focusing on backend and infrastructure topics. Particularly noticeable: None of your last 12 sponsor slots were booked by cloud security providers, although according to our analysis, this category currently achieves the highest CPMs in the tech newsletter segment.”

Why it works: The sender not only read the newsletter, but also carried out a detailed content analysis and related this to competitors and monetization potential.

How we achieve 10-15x deeper personalization at Scalantec

The examples above might sound impressive, but how do you scale such in-depth research for hundreds or thousands of leads? The answer lies in the systematic combination of Technology and Strategic Thinking.

Our process:

Identification of relevant data sources for every target group

  • For e-commerce: store analytics, shipping provider APIs, product catalogs
  • For pharmaceuticals: Clinical Trials Registers, Scientific Papers, Conference Proceedings
  • For publishers: content analysis, ad network data, competitor monitoring
  • For our customers: In a joint consulting process, we determine exactly which data and information is relevant to your target group and how we can best collect it using databases, data craping, AI agents and native capabilities in tools such as Clay

Automated data extraction and analysis with Clay

  • Structured workflows that systematically collect relevant data
  • AI-powered analysis of patterns and anomalies
  • Creating “personalization modules” for every company

Strategic framing of findings by sales experts

  • Transform data into relevant, valuable insights
  • Contextualization in the context of specific industry challenges
  • Formulate convincing entire multi-touch copy including hooks, problem statements and CTAs

The result? Cold emails that are so deeply personalized that they stand out from the mass of generic outreach attempts and achieve significantly higher response rates.

Typical mistakes that ruin 95% of all cold emails

Finally, a look at the most common mistakes we see again and again in cold emails:

1. Superficial pseudo-personalization

The mistake: Repeat obvious information such as name, job title, or company name and sell this as “personalization.”
The solution: Provide in-depth, non-obvious insights that offer the recipient real added value.

2. Jump to the solution too quickly

The mistake: Present your own product immediately without first establishing relevance and understanding.
The solution: First prove that you really understand the problem, then (briefly) outline the solution.

3. Generic claims without proof

The mistake: Make big promises (“we can cut your costs”) without concrete evidence.
The solution: Name specific, measurable results from comparable customers or situations.

4. Too aggressive CTAs

The mistake: Request a meeting or demo right away, or even worse, send a Calendly link.
The solution: Offer low-threshold CTAs that should start a conversation, not close it.

5. Excessive formal or artificial tone

The mistake: Stiff, impersonal language or artificial expressions of enthusiasm.
The solution: Write as you would actually communicate with a colleague — professionally but authentically.

The 3-step process for successful cold emails

Based on our experience with hundreds of outbound campaigns, we have developed a clear 3-step process that consistently leads to above-average results:

Step 1: Deep, strategic research

  • Identify non-obvious information that is relevant to the recipient
  • Look for patterns, anomalies, or inefficiencies in your current setup
  • Find connections between their challenges and your solution

example: Analyze not only the products for an e-commerce shop, but also the margins per category, shipping structures, return rates and competitive positioning.

Step 2: Structured email structure

  • Hook: Show your deep research and understanding instantly
  • Problem: Define a specific challenge that you've identified
  • Solution: Briefly outline how you can help (without promising too much)
  • Proof: Provide a specific example or reference
  • CTA: Provide an easy next step

example: See the “Anatomy of a Perfect Cold Email” above.

Step 3: Systematic testing and optimization

  • A/B testing of various hooks and problem formulations
  • Analysis of response patterns by sector, seniority level and company size
  • Continuous refinement based on feedback and results

example: In a campaign for a SaaS customer, we found that hooks with competitive comparisons performed 3x better among C-level decision makers than at manager level, where technical implementation details were more well received.

Conclusion: Stand out from the crowd through genuine relevance

The art of cold email doesn't lie in clever wording or psychological tricks. It lies in the ability to create real relevance through deep research and to show it to the recipient: “I understand your specific situation and bring valuable insights.”

While 95% of all sales teams continue to rely on superficial personalization and generic messages, this approach allows you to set yourself apart and consistently achieve above-average results.

At Scalantec, we have implemented this process for numerous B2B companies — with consistently higher response rates than traditional outbound methods.

Would you like to learn more about how we can implement this approach for your company? Set up a short conversation with our team. Based on your specific target group, we'll be happy to show you how in-depth research and real relevance can become a game changer for your outbound strategy.

Nicolas Schell is co-founder of Scalantec and an expert in B2B sales and sales automation. With experience from positions at Celonis, Presize and Edgeless Systems, he has developed a practical approach for successful sales campaigns. His particular expertise lies in the use of modern tools such as Clay, with which he develops data-driven processes for lead generation and personalization. Nicolas combines his knowledge in data analysis, prompt engineering and AI to optimize sales processes at the highest level.